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Persons who are affected by the physical symptoms of a disease but do not respond to a drug that alleviates them in others may stand out as different That difference may result in imposed limitations For instance, an individual with epilepsy whose seizures can be controlled by a drug will be able to drive a car and work in a dangerous occupation or workplace, whereas an individual with epilepsy who is not responsive or only partially responsive to that drug may not be allowed to drive a car or be employed in potentially hazardous occupations (Ozuna, 1993) These differences also may be observed through genetic testing for drug response.

approach to the identify phase However, it poses two somewhat different potential problems First, it does not facilitate a clear, sequential focus on performance criteria, which helps to avoid omissions Second, it leaves structural and trade-off issues to be addressed later as they must be for quanti cation, and this can mitigate against appropriate quanti cation By impeding quanti cation, it impairs the iterative process that is central to a complete RMP Much more detailed analysis of objectives, including their decomposition in a structure directly related to project activities or design components, may be useful in some cases For example, in a high-technology product development project, if a set of components is assessed as very risky, it may be possible to design out the uncertainty by changing the basic nature of the design, perhaps as part of a formal value management process (Green, 1994).

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Thus, as it becomes more possible to control everyday risks with pharmacogenomic therapies, it also becomes possible to identify the subgroups of individuals for whom that control is not available and to minimize their risks (and those of others around them) by nonmedical rules and regulations As in the case of disease groups, once drug response groups are imposed, it is likely that some of the persons so categorized will resist their attendant loss of social control (symbolized by their presumed loss of bodily control) by asserting ownership of the drug response identity or by asserting a counter-identity Indeed, studies of minority-majority group relations show that the process of imposed minority status almost always co-occurs.

This will require a clear understanding of the functional role of the components in the overall design It involves an interaction between the project why and what The groundwork for identi cation of such issues should have been provided back in the de ne phase It is important to address these dif culties explicitly as part of the focus phase or the closely linked structure phase Guidance on how to manage such dif culties is beyond the scope of this book, but a starting point for those interested is provided by Chapman et al (1985a), Klein (1993), and Chapman and Ward (2002) Even if only one project party is of concern, it is very important to de ne objectives in writing and their relative priorities Often different parts of the same organization have different objectives At the very least, agreed priorities in terms of time, cost, and performance are essential.

Step 15: Decide How and When Progress Will Be Evaluated and the Plan Will Be Updated In the course of answering the questions above, you ve created a preliminary technology plan Bear in mind that your startup organization has very little experience on which to base a technology program and so you will need to revisit the plan at frequent intervalsYou ve given it your best shot but nonprofit leaders do not arrive equipped with crystal balls Change can be rapid in small nonprofits as personnel changes and priorities are adjustedThat means your technology plan must change too.

If you don't have the necessary resources and available time to perform testing on the project, you are lost! Early test preparation leads to the resources understanding what to do and uncovers possible problems. Ensure the testers stress the limitations of the solution. Tests must be planned by the testers and be synchronized with the overall project schedule. Ensure that the business requirements and project plan are updated to the stage that the testing begins. Incomplete or outdated documentation delays the testing process!

If differences are very important, treating the different parts of the organization as separate partners may be appropriate This takes us into different criteria related to different parties and uncertainty associated with other W s..

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