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3 estrogen (Premarin cream nightly) for 3 to 4 weeks will improve the glycogen content of atrophic mucosa, improving the sensitivity of both colposcopy and Lugol staining. If the patient is allergic to iodine, a 1% aqueous solution of toluidine blue can alternatively be utilized for visualization. The solution is applied to the vagina, allowed to dry for several minutes, and then washed with a 1% to 2% acetic acid solution. Suspected areas of VAIN will stain blue. Unfortunately a high false-positive rate is noted with this method, as areas of in ammation, nonneoplastic ulceration, or excoriation will have high uptake of blue stain. False-negative results are also noted in hyperkeratotic lesions because little dye is absorbed through the layer of hyperkeratotic epithelium. After hysterectomy, lesions in the recesses of the vaginal cuff may be dif cult to visualize by any of these techniques. All visualized acetowhite lesions, and in particular lesions with abnormal vascularity (mosaicism or punctuation), should be biopsied. Multiple small biopsies can be obtained with alligator-jaw forceps. A skin hook may be useful for manipulating the vaginal wall to allow visualization in vaginal folds or recesses caused by scarring from prior hysterectomy. VAIN is more often multifocal than CIN, and a thorough exam of the entire vagina must be undertaken when one lesion is identi ed. The cervix (if present) and vulva should also be evaluated to exclude concurrent lesions. A thorough digital exam should also be performed to examine for thickening, irregularity, or nodularity, and results should be included in documentation of the vaginal evaluation.9 In this patient colposopy identi es a 3 3-cm lesion in the posterior fornix which is faint white in color. Topical benzocaine is applied and a biopsy is obtained. The pathology report is consistent with mild dysplasia (VAIN I).

committed. A pro le of the victims would show the level of risk of becoming a victim for speci c categories of crime. The level of risk would vary by geographic areas across the partnership and by time of day. For example, the level of risk in a busy conurbation shopping area at two o clock in the afternoon would be very different from that at two o clock in the morning, when clubs and pubs are closing. By using the BCS methodology an action plan could be prepared which was truly evidence based. Then performance on the action plan could be monitored by external bodies including the Crime Directors attached to the Government Of ces in the Regions of England and Wales. The crime audits are intended to be conducted on a three-year cycle. The intention would be for all the relevant partners to have achieved a genuine reduction in the level of crimes over that period, as measured by the surveys.

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[73] Pattie Maes, Concepts and experiments in computational re ection, in OOPSLA 87: Conference Proceedings on Object-oriented Programming Systems, Languages and Applications, pp 147 155 ACM Press, 1987 [74] N Malhotra, M Krasniewski, C Yang, S Bagchi and W Chappell, Location Estimation in Ad hoc Networks with Directional Antenna, in Proceedings of the 25th International Conference on Distributed Computing Systems (ICDCS), Columbus, Ohio, June 2005 [75] Pedro Jos Marr n, Andreas Lachenmann, Daniel Minder, J rg H hner, Robert Sauter and Kurt Rothermel, Tinycubus: A exible and adaptive framework for sensor networks, in Erdal ay rc Sebnem Baydere and Paul Havinga, editors, Proc of the 2nd European Workshop on Wireless Sensor Networks, pp 278 289, Istanbul, Turkey, January 2005 [76] Philip K McKinley, S Masoud Sadjadi, Eric P Kasten and Betty HC Cheng, Composing adaptive software, IEEE Computer, pp 56 64, July 2004 [77] Philip K McKinley, S.

Masoud Sadjadi, Eric P Kasten and Betty HC Cheng, A taxonomy of compositional adaptation, Technical Report MSU-CSE-04-17, Department of Computer Science, Michigan State University, East Lansing, Michigan, May 2004 [78] Microsoftnet [79] Com: Delivering on the promises of component technology, 2000 [80] DL Mills, Internet Time Synchronization: the Network Time Protocol, IEEE Trans Communications, vol 39, no 10, pp 1482 1493, October 1991 [81] H Naguib and G Coulouris, Towards Automatically Con gurable Multimedia Applications, in ACM Multimedia Middleware workshop at MM 01, Ottawa, Canada, October 2001 [82] Dushyanth Narayanan, Operating System Support for Mobile Interactive Applications, PhD thesis, School of Computer Science, Computer Science Department, Carniege Melon University, August 2002.

J. J. Duderstadt, The Future of the University: A Perspective from the Oort Cloud, Emory University Futures Forum, Atlanta, GA, March 8, 2005. 10 I. J. Good, Speculations Concerning the First Ultraintelligent Machine, Advances in Computers, Vol. 6, pp. 31 88, Academic Press, San Diego, 1965.

FIGURE 5-1: The BlackBerry Modem Initialization String (for Cingular networks)

[83] Rolf Neugebauer and Derek McAuley, Energy is just another resource: Energy accounting and energy pricing in the Nemesis OS, in Proceedings of the 8th Workshop on Hot Topics in Operating Systems, Schloss Elmau, Germany, May 2001 [84] D Niculescu and B Nath, Position and Orientation in Ad hoc Networks, Journal of Ad Hoc Networks, vol 2, no 2, pp 133 151, April 2004 [85] Brian Noble, M Satyanarayanan, Dushyanth Narayanan, James Tilton, Jason Flinn and Kevin Walker, Agile application-aware adaptation for mobility, in Proceedings of the 16th ACM Symposium on Operating System Principles, St Malo, October 1997 [86] DL Parnas, On the criteria to be used in decomposing systems into modules, Commun ACM, vol 15, no 12, pp 1053 1058, 1972 [87] Adrian Perrig, John Stankovic and David Wagner, Security in wireless sensor networks, Commun ACM, vol 47, no 6, pp 53 57, 2004.

[88] Adrian Perrig, Robert Szewczyk, JD Tygar, Victor Wen and David E Culler, Spins: security protocols for sensor networks, Wirel Netw, vol 8, no 5, pp 521 534, 2002..

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